药物合成、抗肿瘤新药研究和生物医用高分子新材料研究。

1.Copper-catalyzed Reactions Of α,β-unsaturated N-tosylhydrazones With Diaryliodonium Salts To Construct N-arylpyrazoles And Diaryl Sulfone.Org. Biomol. Chem.,2022,20(35):7011-7016.（通讯作者）
2.Direct One-Pot Construction Of Diaryl Thioethers And 1,3-Diynes Through A Copper(I)-Catalyzed Reaction Of λ3-Iodanes With Thiophenols.European J. Org. Chem.,2022,2022(30):e202200613.（通讯作者）
3.Synthesis, Characterization Of Spirocyclic λ3-Iodanes And Their Application To Prepare 4,1-Benzoxazepine-2,5-diones And 1,3-Diynes.Chemistry,2021,27(1期):4312-4316.（通讯作者）
4.A Base-Promoted Cascade Reaction Of α,β-Unsaturated NTosylhydrazones With o-Hydroxybenzyl Alcohols: Highly Regioselective Synthesis Of N-sec-Alkylpyrazoles.Org. Biomol. Chem.,2019,17(30):P8561-8570.（通讯作者）
5.Straightforward Synthesis Of Triester-Substituted Pyrrolizidines By A Three-Component Reaction Of β,γ-Unsaturated α-Keto Esters,Proline, And Maleates.Synlett,2018,29(18):P2390-2395.（通讯作者）
6. An-Jie Xia, Tai-Ran Kang,* Long He,* Lian-Mei Chen, Wen-Ting Li, Jin-Liang Yang and Quan-Zhong Liu,* Metal-Free Ring Expansion Reaction of Six-membered Sulfonylimines with Diazomethanes Generated in Situ from N-Tosylhydrazones: A New Approach toward Seven-membered Enesulfonamides, Angew. Chem. Int. Ed. 2016, 55, 1441-1444.
7. Xufeng Nie, Yachuan Wang, Lijun Yang, Zaijun Yang, and Tairan Kang.*Highly stereoselective synthesis of 1-cyanocyclopropane-carboxamides from 3-substituted-2-cyanoacrylamides with N-tosylhydrazones under metal-free conditions.Tetrahedron Lett. 2017, 58,3003–3007
8. Ying He, Tai-Ran Kang,* Quan-Zhong Liu,* Lian-Mei Chen, Yi-Lian Tu, Tang-Bin Chen, Zhi-Qiang Wang, Jie Liu, Yong-Mei, Xie, Jing-Liang Yang, Long He.*One-pot Synthesis of Optically Enriched 2-Piperidinones from Aliphatic Aldehydes and Cyanoacrylamides, Org. Lett.2013,15, 4054-4057.
9. Yong Liu, Tai-Ran Kang,*Quan-Zhong Liu,*Lian-Mei Chen, Ya-Chuan Wang, Jie Liu, Yong-Mei Xie, Jin-Liang Yang,and Long He.*Enantioselective [4 + 2] Cycloaddition of Cyclic N-Sulfimines and Acyclic Enones or Ynones: A Concise Route to Sulfamidate-Fused 2,6-Disubstituted Piperidin-4-ones, Org. Lett. 2013, 15, 6090-6093.
10. Tai-Ran Kang, Yu Chen, Long He,* Jia Ye, Quan-Zhong Liu.*Facile Synthesis of Highly Functional Pyrrolizidine Derivatives from β,γ-Unsaturated α-Keto Esters and Proline via a Tandem Cycloaddition,Tetrahedron Lett. 2012, 53, 2252-2555.
11. Chun-Hui Ma, Tai-Ran Kang,*Long He,* Quan-Zhong Liu,* Highly Enantioselective Michael Reaction of Malonates to beta-CF3-beta-(3-indolyl) nitroalkenes: Construction of Trifluoromethylated All-Carbon Quaternary Stereogenic Centres, Eur. J. Org. Chem. 2014, 3981-3985
12. Wen-Ke Li, Ze-Shui Liu, Long He,* Tai-Ran Kang,* and Quan-Zhong Liu*,Enantioselective Cycloadditions of Vinyl Cyclopropanes and Nitroolefins for Functionally and Optically Enriched Nitrocyclopentanes, Asian J. Org. Chem., 2015, 4, 28-32.
13. Yong-Mei Xie, Yu-Qin Yao, Hong-Bao Sun, Ting-Ting Yan, Jie Liu,* and Tai-Ran Kang,* Facile Synthesis of Functionalized Spiropyrrolizidine Oxindoles via a Three-Component Tandem Cycloaddition Reaction. Molecules 2011, 16, 8745-8757

在Angewandte Chemie International Edition，Org. Lett等学术期刊发表论文30多篇。主研抗肿瘤新药曲妥珠单抗-美登素偶联物的制备技术转让给国内知名企业；以第一完成人获得发明专利授权1项、受理发明专利3项和市级科技进步奖1项。
科研项目：
1.烷（ 芳） 基重氮甲烷在插入反应和环加成反应中的新应用研究。国家自然科学基金面上项目， 21672172， 2017.01-2020.12，主持。
2.生物医用新材料四川省青年科技创新研究团队。2017TD0008，2017.03-2020.03。团队带头人，主持。在研。
3.抗肿瘤化学新药研发。四川老员工物治疗国家重点实验室项目，主持。
4.高分子生物医用材料的合成及生物医用产品（封闭膜）的研发。横向项目， XTCX2014003， 2014.01-2018.12，主持。
5.美登素偶联物的合成及活性研究。中国博士后科学基金面上项目，2012M511933，2013.01-2014.12，主持。
6.肿瘤靶向治疗弹头药物—美登素的修饰物化学合成研究。四川省科技厅应用基础研究项目， 2013JY0095， 2013.01-2015.12， 主持。
7.新型聚氨酯类材料设计合成和生物相容性评价及其生物医用产品的研发。四川省教育厅重大培育项目， 15CZ0016， 2015.01-2017.12，主持。
8.肿瘤靶向治疗候选药物抗 FAP 单链抗体-美登素偶联物的研发。科技部国家新药创制重大专项，2012ZX09103-301-030，2012.01-2015.12，副组长，主研。
9.肿瘤靶向治疗候选药物曲妥珠单抗-美登素偶联物的研发。 横向项目， 2012.01-2014.12，副组长，主研。